RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-326
RNA ID
MI0000598
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
RT-PCR; dual-luciferase reporter assay
Target
FCgamaRIII
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
28921768
Title
MicroRNA-326-3p ameliorates high glucose and ox-LDL-IC- induced fibrotic injury in renal mesangial cells by targeting FcgamaRIII
Year
2018
Function
miR-326-3p/TGF-beta/smad signaling pathway was investigated to be involved in the pathophysiology of renal fibrosis of diabetic kidney disease (DKD).